395 research outputs found

    The relationship between learning style preferences and academic achievement of English majors at al-Aqsa University in Gaza, Palestine

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    This study aims to investigate the relationship between the learning style preferences, and academic achievement of third year English majors at Al Aqsa University in Gaza, Palestine. A total of 60 students were asked to complete a questionnaire to identify their perceptual learning style preferences. In addition, an achievement test was held to determine the students' academic level in English and the results were correlated with the learning style preferences. The findings showed that the top two learning styles preferred were kinesthetic, 90.27% and tactile learning 82.27% respectively. The other learning styles preferred in decreasing popularity were the group learning style 79.80%, visual style 78.80%, auditory style 78.60% and individual learners 54.73%. Moreover, there were statistically significant differences between males and females in visual, auditory, individual learning, and group learning, and there were no statistically significant differences between males and females in kinaesthetic and tactile. Furthermore, there was a significant correlation between achievement and auditory style, but there was no significant correlation between achievement and visual, kinaesthaetic, tactile, group learning, and individual learning. The paper ends with a discussion of some pedagogical implications of the findings on tertiary education in the local context

    Turbulent mixing of particles under tidal bores: An experimental analysis

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    A tidal bore develops in an estuary when the tidal range exceeds 4.5-6 m and the estuarine bathymetry amplifies the tidal wave. The bore is an abrupt rise in water depth associated with a discontinuity in velocity and pressure fields at the front. Herein the free-surface properties and the turbulent mixing of light-weight particles were investigated during the passage of tidal bores. The free-surface properties were recorded using a non-intrusive technique, while particle tracking was performed under undular and breaking bores. A basic result was the identification of a broad spectrum of particle trajectories, linked with the existence of large-scale vortical structures. These turbulent structures were responsible for the vertical water mixing as a tidal bore propagates upstream in an estuary. The large-scale eddies were also responsible for the rapid longitudinal dispersion of particulates, such as fish eggs, with some form of preferential motion, depending upon the particle's vertical elevation

    The predominant learning approaches of medical students

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    Background By identifying medical students’ learning approaches and the factors that influence students’ learning approaches, medical schools and health care institutions are better equipped to intervene and optimize their learning experience. The aims of our study is to determine the predominant learning approach amongst medical students on a clinical posting in a hospital in Singapore and to examine the demographic factors that affect their learning approach. Methods The Approaches and Study Skills Inventory for Students (ASSIST) questionnaire was administered to 250 medical students from various medical schools on clinical attachment to the Obstetrics and Gynaecology (O&G) department of KK Women’s and Children’s Hospital (KKH) Singapore between March 2013 and May 2015 to determine students’ predominant learning approaches. Multinomial logistic regression was used to examine the association between demographic factors (age, gender and highest education qualification) and predominant learning approach. A cut-off of p \u3c 0.05 was used for statistical significance. Results Amongst 238 students with one predominant learning approach, 96 (40.3%) and 121 students (50.8%) adopted the deep and strategic approach respectively, whilst only 21 (8.8%) adopted the surface approach. Male students appeared less likely to adopt the strategic learning approach than female students (p value = 0.06). Predominant learning approaches were not influenced by demographic characteristics such as age, gender and highest educational qualifications. Conclusions This study provided insight into the learning approaches of a heterogeneous group of medical students in Singapore. While it is encouraging that the majority of students predominantly utilised the deep and strategic learning approach, there was a significant proportion of students who utilised the surface approach. Interventions can be explored to promote deeper learning amongst these students

    Broadband teleportation

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    Quantum teleportation of an unknown broadband electromagnetic field is investigated. The continuous-variable teleportation protocol by Braunstein and Kimble [Phys. Rev. Lett. {\bf 80}, 869 (1998)] for teleporting the quantum state of a single mode of the electromagnetic field is generalized for the case of a multimode field with finite bandwith. We discuss criteria for continuous-variable teleportation with various sets of input states and apply them to the teleportation of broadband fields. We first consider as a set of input fields (from which an independent state preparer draws the inputs to be teleported) arbitrary pure Gaussian states with unknown coherent amplitude (squeezed or coherent states). This set of input states, further restricted to an alphabet of coherent states, was used in the experiment by Furusawa {\it et al.} [Science {\bf 282}, 706 (1998)]. It requires unit-gain teleportation for optimizing the teleportation fidelity. In our broadband scheme, the excess noise added through unit-gain teleportation due to the finite degree of the squeezed-state entanglement is just twice the (entanglement) source's squeezing spectrum for its ``quiet quadrature.'' The teleportation of one half of an entangled state (two-mode squeezed vacuum state), i.e., ``entanglement swapping,'' and its verification are optimized under a certain nonunit gain condition. We will also give a broadband description of this continuous-variable entanglement swapping based on the single-mode scheme by van Loock and Braunstein [Phys. Rev. A {\bf 61}, 10302 (2000)]Comment: 27 pages, 7 figures, revised version for publication, Physical Review A (August 2000); major changes, in parts rewritte

    Differential osteogenic activity of osteoprogenitor cells on HA and TCP/HA scaffold of tissue engineered bone.

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    Biomaterial, an essential component of tissue engineering, serves as a scaffold for cell attachment, proliferation, and differentiation; provides the three dimensional (3D) structure and, in some applications, the mechanical strength required for the engineered tissue. Both synthetic and naturally occurring calcium phosphate based biomaterial have been used as bone fillers or bone extenders in orthopedic and reconstructive surgeries. This study aims to evaluate two popular calcium phosphate based biomaterial i.e., hydroxyapatite (HA) and tricalcium phosphate/hydroxyapatite (TCP/HA) granules as scaffold materials in bone tissue engineering. In our strategy for constructing tissue engineered bone, human osteoprogenitor cells derived from periosteum were incorporated with human plasma-derived fibrin and seeded onto HA or TCP/HA forming 3D tissue constructs and further maintained in osteogenic medium for 4 weeks to induce osteogenic differentiation. Constructs were subsequently implanted intramuscularly in nude mice for 8 weeks after which mice were euthanized and constructs harvested for evaluation. The differential cell response to the biomaterial (HA or TCP/HA) adopted as scaffold was illustrated by the histology of undecalcified constructs and evaluation using SEM and TEM. Both HA and TCP/HA constructs showed evidence of cell proliferation, calcium deposition, and collagen bundle formation albeit lesser in the former. Our findings demonstrated that TCP/HA is superior between the two in early bone formation and hence is the scaffold material of choice in bone tissue engineering

    Lack of correlation of stem cell markers in breast cancer stem cells

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    BACKGROUND: Various markers are used to identify the unique sub-population of breast cancer cells with stem cell properties. Whether these markers are expressed in all breast cancers, identify the same population of cells, or equate to therapeutic response is controversial. METHODS: We investigated the expression of multiple cancer stem cell markers in human breast cancer samples and cell lines in vitro and in vivo, comparing across and within samples and relating expression with growth and therapeutic response to doxorubicin, docetaxol and radiotherapy. RESULTS: CD24, CD44, ALDH and SOX2 expression, the ability to form mammospheres and side-population cells are variably present in human cancers and cell lines. Each marker identifies a unique rather than common population of cancer cells. In vivo, cells expressing these markers are not specifically localized to the presumptive stem cell niche at the tumour/stroma interface. Repeated therapy does not consistently enrich cells expressing these markers, although ER-negative cells accumulate. CONCLUSIONS: Commonly employed methods identify different cancer cell sub-populations with no consistent therapeutic implications, rather than a single population of cells. The relationships of breast cancer stem cells to clinical parameters will require identification of specific markers or panels for the individual cancer

    Prescribing patterns of low doses of antipsychotic medications in older Asian patients with schizophrenia, 2001-2009

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    Background: This study examined the use of low doses of antipsychotic medications (300mg/day CPZeq or less) in older Asian patients with schizophrenia and its demographic and clinical correlates. Methods: Information on hospitalized patients with schizophrenia, aged 55 years or older, was extracted from the database of the Research on Asian Psychotropic Prescription Patterns (REAP) study (2001-2009). Data on 1,452 patients in eight Asian countries and territories including China, Hong Kong, Japan, Korea, Singapore, Taiwan, India, and Malaysia were analyzed. Sociodemographic and clinical characteristics and antipsychotic prescriptions were recorded using a standardized protocol and data collection procedure. Results: The prescription frequency for low doses of antipsychotic medications was 40.9% in the pooled sample. Multiple logistic regression analysis of the whole sample showed that patients on low doses of antipsychotic medications were more likely to be female, have an older age, a shorter length of illness, and less positive symptoms. Of patients in the six countries and territories that participated in all the surveys between 2001 and 2009, those in Japan were less likely to receive low doses of antipsychotics. Conclusion: Low doses of antipsychotic medications were only applied in less than half of older Asian patients with schizophreni

    Synthetic Mimic of Antimicrobial Peptide with Nonmembrane-Disrupting Antibacterial Properties

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    Proteolysis in dairy lactic acid bacteria has been studied in great detail by genetic, biochemical and ultrastructural methods. From these studies the picture emerges that the proteolytic systems of lactococci and lactobacilli are remarkably similar in their components and mode of action. The proteolytic system consists of an extracellularly located serine-proteinase, transport systems specific for di-tripeptides and oligopeptides (> 3 residues), and a multitude of intracellular peptidases. This review describes the properties and regulation of individual components as well as studies that have led to identification of their cellular localization. Targeted mutational techniques developed in recent years have made it possible to investigate the role of individual and combinations of enzymes in vivo. Based on these results as well as in vitro studies of the enzymes and transporters, a model for the proteolytic pathway is proposed. The main features are: (i) proteinases have a broad specificity and are capable of releasing a large number of different oligopeptides, of which a large fraction falls in the range of 4 to 8 amino acid residues; (ii) oligopeptide transport is the main route for nitrogen entry into the cell; (iii) all peptidases are located intracellularly and concerted action of peptidases is required for complete degradation of accumulated peptides.
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